Cold and distant: structural features of the nucleoprotein complex of a cold-adapted influenza A virus strain

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Development and Sequence Analysis of a Cold-Adapted Strain of Influenza A/New Caledonia/20/1999(H1N1) Virus

Background and Aims: Vaccination is the most effective method to prevent influenza infection. Among the available vaccines, cold-adapted live-virus vaccines are suitable approach that have been produced and evaluated for recent years in few countries. The goal of this project was to derivate a cold adapted variant of the influenza A/New Caledonia/20/1999(H1N1). Materials and Methods: Influenza ...

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15 صفحه اول

development and sequence analysis of a cold-adapted strain of influenza a/new caledonia/20/1999(h1n1) virus

background and aims: vaccination is the most effective method to prevent influenza infection. among the available vaccines, cold-adapted live-virus vaccines are suitable approach that have been produced and evaluated for recent years in few countries. the goal of this project was to derivate a cold adapted variant of the influenza a/new caledonia/20/1999(h1n1). materials and methods: influenza ...

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Cold-adapted variants of influenza virus A. I. Comparison of the genetic properties of ts mutants and five cold-adapted variants of influenza virus A.

The genetic properties of seven cold-adapted variants of influenza virus A were compared with those of nine Lfluorouracil (5-FU)-induced ts mutants. The 5-FU mutants had previously been placed into seven complementation-recombination groups; five of the seven cold-adapted variants also had the ts phenotype, and all five were shown to share the group 1 lesion. Three of the cold variants also had...

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ژورنال

عنوان ژورنال: Journal of Biomolecular Structure and Dynamics

سال: 2020

ISSN: 0739-1102,1538-0254

DOI: 10.1080/07391102.2020.1776636